Gordon Holmes lecture: Gordon Holmes and the neurological heritage

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Gordon Holmes Lecture: Gordon Holmes and the neurological heritage.

Sir Gordon Holmes is one of the great figures in the history of twentienth century neurology. In him, there came together the traditions of German and British neurology which moulded a physiological approach to normal and disordered function of the nervous system with a commitment to interpreting clinical phenomena in the light of meticulous pathological examination. He, more than any other ind...

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Sir Gordon Holmes.

FORTY MILES from Dublin at Castlebellingham on the coast of Co. Louth, Gordon Morgan Holmes was born in Dillon House on 22 February 1876. A scholar at Trinity College Dublin, he graduated B.A. in 1897, being senior moderator and gold medallist, and qualified in medicine the following year. After serving as a resident medical officer in the Richmond Asylum (now St. Brendan's Hospital), he studie...

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Selected papers of Gordon Holmes

the subjective perception of neurological deficit; and with the disorders of vision. Thus, one essay examines sociological aspects of aphasia, another the detection of minimal dysphasia, and others the evolution and possible future of language. His exploration of the relationship between the language of schizophrenics and that of aphasics is particularly fascinating. Other essays deal with miso...

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PNPLA6 mutations cause Boucher-Neuhauser and Gordon Holmes syndromes as part of a broad neurodegenerative spectrum.

Boucher-Neuhäuser and Gordon Holmes syndromes are clinical syndromes defined by early-onset ataxia and hypogonadism plus chorioretinal dystrophy (Boucher-Neuhäuser syndrome) or brisk reflexes (Gordon Holmes syndrome). Here we uncover the genetic basis of these two syndromes, demonstrating that both clinically distinct entities are allelic for recessive mutations in the gene PNPLA6. In five of s...

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Holmes

The European Research Council has recently funded HOLMES, a new experiment to directly measure the neutrino mass. HOLMES will perform a calorimetric measurement of the energy released in the decay of 163Ho. The calorimetric measurement eliminates systematic uncertainties arising from the use of external beta sources, as in experiments with beta spectrometers. This measurement was proposed in 19...

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ژورنال

عنوان ژورنال: Brain

سال: 2006

ISSN: 0006-8950,1460-2156

DOI: 10.1093/brain/awl335